Synthetic VDRL Antigen

For more than a decade, Arlington Scientific has worked closely with the Centers for Disease Control and Prevention to provide CDC licensed Synthetic VDRL. Our ASI product is FDA cleared (K993633) and is substantially equivalent to traditional VDRL manufactured by other companies. This synthetic VDRL is environmentally friendly and is manufactured using synthetic Cardiolipin and synthetic Lecithin. Traditional VDRL’s manufacturing process is complex and toxic. This synthetic VDRL test can be used to test if syphilis has involved the central nervous system (Neurosyphilis) by testing cerebral spinal fluid (CSF).

Limited Utility of Reverse Algorithm Syphilis Testing

A study presented in the journal Sexually Transmitted Diseases suggested that the reverse algorithm for syphilis testing is inefficient in populations with a high prevalence of syphilis. The study also stated that “limitations of the reverse algorithm included cost effectiveness and false positivity. This contributes to unnecessary costs, discomfort, and potential impacts on sex partners. False positives also create an additional burden for clinical staff and public health professionals.”